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However, when given in equivalent doses, Bumex and Lasix have similar overall effectiveness Indapamide (Lozol) is a new diuretic and antihypertensive agent. Lasix may be used with antihypertensive drugs to control high blood pressure (hypertension) Thiazide diuretics are an FDA-approved class of drugs that inhibit the reabsorption of 3% to 5% of luminal sodium in the distal convoluted tubule of the nephron. Lasix is a type of “loop” diuretic while thiazides refer to a class of diuretics. The drug appears to have a unique mechanism of action, combining diuretic effects with a direct vascular action, presumably secondary to calcium channel blockade. Lasix and thiazides are diuretics (water pills) used to treat excess accumulation of fluid or swelling of the body ( edema) caused by heart failure, kidney disease, chronic kidney failure, or liver disease. Lasix is a brand name for furosemide.. Bumex is a more potent diuretic than Lasix. Available studies indicate that indapamide is comparable to hydrochlorothiazide, chlorothiazide, furosemide, and other. The absorption of Bumex is also more predictable than that of Lasix. Lasix and thiazides are different types of diuretics Thiazide diuretics are a type of diuretic (a drug that increases urine flow). It takes a larger dose of Lasix to achieve the same effect as a lower dose of Bumex. Lasix and thiazides are also used to treat high blood pressure ( hypertension ). By doing so, thiazide diuretics promote natriuresis and diuresis.